Neurologic Complications of Extracorporeal Cardiopulmonary Resuscitation in Neonates and Infants

Objective: Extracorporeal membrane oxygenation (ECMO) is a lifesaving measure for patients in cardiac or respiratory failure. cardiopulmonary resuscitation (ECPR) emergent ECMO cannulation during arrest. All are at high risk neurologic complications, but the degree of ECPR relative to without CPR progress (non-ECPR ECMO) not well documented infants. The goal present study compare complication rates between infants who underwent and those non-ECPR ECMO. Methods: We performed retrospective chart review on all admitted 2009 2020 neonatal intensive care unit (NICU) our quaternary children's hospital. separated by vs. cannulation. compared death used neuroimaging video electroencephalogram (vEEG) determine incidence stroke, intracranial hemorrhage, seizure. Chi-square Fisher's exact tests were these categorical variables among groups.Results: A total 181 cannulated onto Of these, 40 received ECPR, 56 indication, 85 indication. After excluding currently (n=1, ECPR), 180 subjected analysis. less likely survive hospital discharge than indications, any with indications. Interpretation: Significantly fewer survived experiencing complication, patients.